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RECRUITING
NCT04462978

Non-Immunoglobulin E-mediated Food Allergies in Children

Sponsor: Federico II University

View on ClinicalTrials.gov

Summary

Non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFA) are an evolving web of clinical conditions characterized by subacute and/or chronic symptoms and include food protein-induced enterocolitis syndrome (FPIES), food protein-induced enteropathy (FPE), food protein-induced allergic proctocolitis (FPIAP), and food protein-induced allergic dysmotility disorders (gastroesophageal reflux disease (GERD), colic and constipation) (FPIMD). Despite the prevalence and clinical impact of these conditions, the pathogenesis as well as the natural history and the best management of these disorders are still poorly defined. These limitations could be responsible for diagnostic delays and errors, and suboptimal clinical management. We aim to evaluate clinical features, natural course and pathophysiology of non-IgE-GIFA in the pediatric age.

Official title: Investigating Clinical Features, Natural Course and Pathophysiology of Non-Immunoglobulin E-mediated Food Allergies in the Pediatric Age

Key Details

Gender

All

Age Range

1 Day - 14 Years

Study Type

OBSERVATIONAL

Enrollment

150

Start Date

2017-01-01

Completion Date

2027-12-28

Last Updated

2026-09-02

Healthy Volunteers

Yes

Interventions

OTHER

Non IgE-mediated food allergy

Locations (1)

University of Naples Federico II

Naples, Italy