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RECRUITING
NCT04469504
NA

Preoperative Prehabilitation for Sarcopenic Patients Prior to Pancreatic Surgery for Cancer

Sponsor: University Hospital, Lille

View on ClinicalTrials.gov

Summary

Major digestive surgery is associated with a significant rate of postoperative complications. To improve postoperative outcome, efforts are focused on postoperative course leading to the concept of rehabilitation. However, the rehabilitation concept does not allow to improve muscular and functional reserves at the time of surgery. Sarcopenia is a condition characterized by loss of skeletal muscle mass and function. Also, the prevalence of sarcopenia in patients with cancer is high and has a prevalence of around 25% in patients with pancreatic cancer, with a considerable impact on postoperative and survival outcomes. The hypothesis is the preoperative management of sarcopenia by a rehabilitation program could improve patients' operative outcomes by reducing the rate of postoperative complications.

Official title: Prehabilitaion Program for Sarcopenic Patients Prior to Pancreaticoduodenectomy for Periampullary Malignant Tumors

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

158

Start Date

2022-05-17

Completion Date

2028-05

Last Updated

2023-02-08

Healthy Volunteers

No

Interventions

OTHER

Prehabilitation program

4-week trimodal prehabilitation program: Exercise, nutritional supplementation, and psychological support

DIETARY_SUPPLEMENT

Oral Impact

perioperative immunonutrition by ORAL IMPACT

Locations (1)

Hop Claude Huriez Chu Lille

Lille, France