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Information About Alzheimer's Disease for Latinos in New York City
Sponsor: Columbia University
Summary
This study will assess the psychosocial and behavioral impacts of receiving Alzheimer's disease genetic risk assessment incorporating APOE genotypes among Latinos in northern Manhattan. The investigators will conduct a longitudinal, community-based study with a mixed methods design. Participants will be randomized to learn about their lifetime risk of late-onset Alzheimer's disease (AD) based either on (a) Latino ethnicity and family history alone (genotype nondisclosure group), or (b) the same factors plus APOE genotype (genotype disclosure group). Responses will be evaluated at 6 weeks, 9 months, and 15 months after risk assessment. In the quantitative component of the study, the investigators will assess psychosocial outcomes, memory test performance, and health-related behaviors. In the qualitative component of the study, the investigators will investigate the lived experience of receiving personal AD risk information, using a stress and coping theoretical framework.
Official title: The IDEAL Study: Information About Alzheimer's Disease for Latinos in New York City
Key Details
Gender
All
Age Range
40 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
374
Start Date
2021-08-13
Completion Date
2025-10-03
Last Updated
2026-10-16
Healthy Volunteers
No
Conditions
Interventions
Disclosure of APOE genotype
Information about risk of Alzheimer's disease will be given to participants based on their APOE genotypes, in addition to Latino ethnicity and family history.
Locations (1)
Columbia University Irving Medical Center
New York, New York, United States