Clinical Research Directory

Inclusion Criteria: * Adults between 18 and 100 years; * At-Risk for RA, RA diagnosed, and Healthy Control subjects will be included in the study until recruitment goals are met for each group. At-Risk: 1. No evidence of inflammatory arthritis on clinical examination AND 2. At elevated risk for RA based on familial or serologic risk * Familial risk includes having a first degree relatives (FDRs) with RA * Serologic risk includes asymptomatic serum ACPA positivity Healthy Controls : 1. No history of RA 2. No FDRs with RA 3. No systemic use of immunosuppressants for autoimmune disease RA Diagnosis: 1. Classified RA by 1987 ACR and/or 2010 ACR/EULAR RA classification criteria (confirmed by medical chart review) OR 2. Diagnosed with RA by a board-certified rheumatologist (confirmed by medical chart review) Exclusion Criteria: 1. Currently pregnant or planning to become pregnant during the sample collection period of the study 2. Exacerbation of underlying obstructive lung disease within the past 1 month 3. Known FEV1 \<1 liter 4. Oxygen requirement \>2 liters at rest 5. Participants with health acuity or behavioral health concerns leaving them unable to participate in the current research Note: If a subject temporarily does not meet inclusion criteria but is interested in participating, he/she may participate once inclusion criteria have been met. If interested, please take a few minutes to complete the screening questionnaire for this study opportunity. You may open the survey in your web browser by clicking the link below: https://is.gd/SPAROscreen If the link above does not work, try copying the link below into your web browser: https://redcap.ucdenver.edu/surveys/?s=3WM8WH3WKK