Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT04482673
PHASE4

Vitamin D Supplementation in the Prevention and Mitigation of COVID-19 Infection

Sponsor: Medical University of South Carolina

View on ClinicalTrials.gov

Summary

The purpose of this study is to evaluate how useful vitamin D supplementation is in reducing the severity of COVID-19 symptoms and the body's inflammatory and infection-fighting response to COVID-19. Individuals ≥50 years of age and older who are tested for COVID-19 and negative will be randomized (like flipping a coin) to either daily high dose vitamin D supplementation (6000 IU vitamin D3/day) vs. standard of care. Those individuals ≥50 years of age or older who test positive for COVID-19 at baseline will be randomized to bolus vitamin D (20,000 IU/day for 3 days) followed by high dose (6000 IU vitamin D/day) vs. standard of care for 12 months. All participants will receive a multivitamin containing vitamin D.

Official title: The Role of Vitamin D in Mitigating COVID-19 Infection Severity: Focusing on Reducing Health Disparities in South Carolina

Key Details

Gender

All

Age Range

50 Years - Any

Study Type

INTERVENTIONAL

Enrollment

95

Start Date

2020-07-31

Completion Date

2023-12-31

Last Updated

2023-02-24

Healthy Volunteers

Yes

Interventions

DRUG

Daily Vitamin D3

6000 IU vitamin D3 daily

DRUG

Daily placebo

Placebo daily

DRUG

Bolus vitamin D3

Bolus 20,000 IU vitamin D3 daily for 3 days

DRUG

Bolus placebo

Bolus placebo daily for 3 days

Locations (1)

Medical University of South Carolina

Charleston, South Carolina, United States