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Vitamin D Supplementation in the Prevention and Mitigation of COVID-19 Infection
Sponsor: Medical University of South Carolina
Summary
The purpose of this study is to evaluate how useful vitamin D supplementation is in reducing the severity of COVID-19 symptoms and the body's inflammatory and infection-fighting response to COVID-19. Individuals ≥50 years of age and older who are tested for COVID-19 and negative will be randomized (like flipping a coin) to either daily high dose vitamin D supplementation (6000 IU vitamin D3/day) vs. standard of care. Those individuals ≥50 years of age or older who test positive for COVID-19 at baseline will be randomized to bolus vitamin D (20,000 IU/day for 3 days) followed by high dose (6000 IU vitamin D/day) vs. standard of care for 12 months. All participants will receive a multivitamin containing vitamin D.
Official title: The Role of Vitamin D in Mitigating COVID-19 Infection Severity: Focusing on Reducing Health Disparities in South Carolina
Key Details
Gender
All
Age Range
50 Years - Any
Study Type
INTERVENTIONAL
Enrollment
95
Start Date
2020-07-31
Completion Date
2023-12-31
Last Updated
2023-02-24
Healthy Volunteers
Yes
Interventions
Daily Vitamin D3
6000 IU vitamin D3 daily
Daily placebo
Placebo daily
Bolus vitamin D3
Bolus 20,000 IU vitamin D3 daily for 3 days
Bolus placebo
Bolus placebo daily for 3 days
Locations (1)
Medical University of South Carolina
Charleston, South Carolina, United States