Clinical Research Directory

Inclusion Criteria: * Cushing\'s disease diagnosed and treated with transsphenoid surgery at study centers Exclusion Criteria: 1. History of VTE before surgery or within 24 hours post-surgery 2. Acute bacterial endocarditis 3. Major bleeding events 4. Thrombocytopenia 5. Active gastrointestinal ulcers 6. History of stroke 7. High risk of bleeding due to clotting abnormalities 8. Participation in other clinical trials within the last three months 9. Contraindications to rivaroxaban (e.g., renal dysfunction with eGFR \< 50 mL/min) 10. Presence of other malignant diseases 11. Severe mental or neurological disorders 12. Presence of intracranial vascular abnormalities 13. Contraindications to mechanical prophylactic anticoagulation 14. Pregnancy 15. Any other condition that researchers deem inappropriate for study participation.