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NOT YET RECRUITING
NCT04488224
EARLY_PHASE1

Nano-X Image Guidance: CBCT With Gravity-induced Motion

Sponsor: University of Sydney

View on ClinicalTrials.gov

Summary

A pilot stage, device feasibility trial, to investigate the feasibility of acquiring cone beam computed tomography (CBCT) images for image guidance for radiation therapy by maintaining a fixed imaging system and rotating the participant about the horizontal axis using the Nano-X patient rotation system. It is a single-arm, controlled, single-blinded, non-treatment, non-invasive, single-institution trial.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2025-09-01

Completion Date

2026-12

Last Updated

2025-08-13

Healthy Volunteers

No

Conditions

Interventions

DEVICE

Nano-X Patient Rotation System

The Nano-X prototype is a horizontal patient rotation system that immobilises participants while being rotated on the horizontal axis. This device will be used to rotate patients horizontally while cone-beam Computed Tomography (CBCT) projections are acquired.

RADIATION

Conventional CBCT scan

A conventional cone-beam Computed Tomography (CBCT) scan is acquired on standard radiotherapy machinery.

OTHER

Psychometrically validated questionnaires

The Claustrophobia Questionnaire (CLQ), Short Form State/Trait Anxiety inventory (STAI) and Fast Motion Sickness (FMS) questionnaires administered. CLQ only once before the first session, STAI and FMS both before and after each Nano-X CBCT session.