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Analysis of Coronavirus Disease 19 (COVID-19) Convalescent Plasma
Sponsor: City of Hope Medical Center
Summary
Plasma from patients who have recovered from coronavirus disease 2019 (COVID-19) is referred to as COVID-19 convalescent plasma (CCP), and may contain antibodies against SARS-CoV-2, the virus responsible for COVID-19. CCP infusion is being evaluated as a therapeutic or prophylactic approach in COVID-19 patients. The goal of this study is to help develop a bank of convalescent plasma in California, especially in medically underserved communities particularly affected by the disease. In parallel, CCP administered to COVID-19 patients will be collected and analyzed to determine whether the antibody profile correlates with clinical outcome. The purpose of this non-therapeutic study is to learn more about the CCP antibody profile and the effect it may have in treating COVID-19 infection.
Official title: Evaluation of Coronavirus Disease 19 (COVID-19) Convalescent Plasma
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
95
Start Date
2020-07-13
Completion Date
2026-10-13
Last Updated
2025-12-05
Healthy Volunteers
Yes
Conditions
Interventions
Biospecimen Collection
Undergo collection of blood and/or nasopharyngeal swabs
Diagnostic Laboratory Biomarker Analysis
Correlative studies
Electronic Health Record Review
Donors and recipients have their medical records reviewed.
Questionnaire Administration
Ancillary studies
Locations (1)
City of Hope Medical Center
Duarte, California, United States