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Lymphatic Mapping Of Oropharyngeal Cancer
Sponsor: University College, London
Summary
A multi-centre validation study to evaluate whether a new imaging and surgical protocol would work as well as the current gold standard in identifying sentinel nodes in patients with oropharyngeal cancer.
Official title: Prospective, Multi-Centre, Phase II Validation Study for a Lymphatic Imaging Protocol in Establishing Drainage Patterns in Patients With Oropharyngeal Cancer
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2022-07-07
Completion Date
2027-01
Last Updated
2024-09-19
Healthy Volunteers
No
Conditions
Interventions
Imaging procedure
During routine examination under anaesthetic 4 x peritumoural injection of investigator's choice of 99mTc-human albumin colloidal particles or Lymphoseek (lymphatic mapping tracer) followed by freehand SPECT scan
Surgical procedure
Excision of contralateral nodes identified on imaging \*(fhSPECT or SPECT/CT\*) during routine examination under anaesthetic. Serial sectioning of excised (sentinel) nodes to identify micrometastasis.
Locations (2)
St George's University Hospitals NHS Foundation Trust
London, United Kingdom
University College Hospital
London, United Kingdom