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COMPLETED
NCT04502095
PHASE4

Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy

Sponsor: Roswell Park Cancer Institute

View on ClinicalTrials.gov

Summary

This trial investigates whether a one-month course of preventative (prophylactic) antibiotics helps to reduce urinary tract infections after robot-assisted surgery to remove all of the bladder as well as nearby tissues and organs (radical cystectomy). Urinary tract infections are a common occurrence after robot-assisted radical cystectomy. Antibiotics such as trimethoprim-sulfamethoxazole or nitrofurantoin may prevent or control infections in patients with urinary tract infection and may help improve their response to radical cystectomy. Information gained from this study may help researchers to predict patient complications and identify better ways to manage these complications.

Official title: Does Prophylactic Antibiotic Decrease the Rate of Urinary Tract Infection After Robot Assisted Radical Cystectomy

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

89

Start Date

2020-09-02

Completion Date

2025-03-13

Last Updated

2026-09-29

Healthy Volunteers

No

Interventions

DRUG

Clindamycin

Given PO

OTHER

Diary

Complete drug diary

DRUG

Ertapenem

Given PO

DRUG

Levofloxacin

Given PO

DRUG

Nitrofurantoin

Given PO

DRUG

Trimethoprim-Sulfamethoxazole

Given PO

Locations (1)

Roswell Park Cancer Institute

Buffalo, New York, United States