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Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy
Sponsor: Roswell Park Cancer Institute
Summary
This trial investigates whether a one-month course of preventative (prophylactic) antibiotics helps to reduce urinary tract infections after robot-assisted surgery to remove all of the bladder as well as nearby tissues and organs (radical cystectomy). Urinary tract infections are a common occurrence after robot-assisted radical cystectomy. Antibiotics such as trimethoprim-sulfamethoxazole or nitrofurantoin may prevent or control infections in patients with urinary tract infection and may help improve their response to radical cystectomy. Information gained from this study may help researchers to predict patient complications and identify better ways to manage these complications.
Official title: Does Prophylactic Antibiotic Decrease the Rate of Urinary Tract Infection After Robot Assisted Radical Cystectomy
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
89
Start Date
2020-09-02
Completion Date
2025-03-13
Last Updated
2026-09-29
Healthy Volunteers
No
Interventions
Clindamycin
Given PO
Diary
Complete drug diary
Ertapenem
Given PO
Levofloxacin
Given PO
Nitrofurantoin
Given PO
Trimethoprim-Sulfamethoxazole
Given PO
Locations (1)
Roswell Park Cancer Institute
Buffalo, New York, United States