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Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure
Sponsor: Vanderbilt University Medical Center
Summary
Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is effective at lowering supine blood pressure, these approaches may be utilized to treat supine hypertension non-pharmacologically. Raising the head of the bed decreases the amount of blood returning to the heart due to the effects of gravity. In this case, the decreased blood return to the heart may decrease blood pressure.
Official title: Impact of Decreased Venous Return on Supine Blood Pressure
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
44
Start Date
2020-08-21
Completion Date
2026-12-31
Last Updated
2025-11-06
Healthy Volunteers
No
Conditions
Interventions
Tilt
Tilt of the whole bed so that the head is elevated by 9 and/or 12 inches in an acute trial or overnight.
Elevated trunk
Elevation of the trunk through raising just the head of the bed until the head is elevated by 9 and/or 12 inches in an acute trial or overnight.
Tilt - In home
Tilt of the whole bed so that the head is elevated by 8 inches overnight.
Elevated Trunk - In home
Elevation of the trunk through raising the head 8 inches on a wedge pillow overnight.
Locations (1)
Vanderbilt University Medical Center
Nashville, Tennessee, United States