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Hypofractionated Radiotherapy Followed by Surgical Resection in the Treatment of Soft Tissue Sarcomas
Sponsor: Vanderbilt-Ingram Cancer Center
Summary
The trial will use neoadjuvant hypofractionated radiotherapy followed by surgical resection in the treatment for soft tissue sarcoma. It will allow patients to be treated over a shorter course (5 or 15 days of radiation) compared to the traditional 5 week regimen. It is proposed that this will be possible without increasing the risk of wound complication or local recurrence compared with a traditional 5 week course of pre-operative radiation.
Official title: Prospective Observational Trial of Two Neoadjuvant Hypofractionated Radiotherapy Regimens Followed by Surgical Resection in the Treatment of Soft Tissue Sarcomas
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2021-03-02
Completion Date
2027-06
Last Updated
2025-03-28
Healthy Volunteers
No
Conditions
Interventions
Ultra-Hypo-fractionation Radiotherapy
Five fractions of pre-operative radiation
Resection
Surgery
Questionnaire Administration
Ancillary studies
Moderately-Hypo-fractionation Radiotherapy
15 fractions of pre-operative radiation
Locations (1)
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, United States