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COMPLETED
NCT04512690
NA

Spinal Cord Stimulation for Restoration of Arm and Hand Function in People With Subcortical Stroke

Sponsor: Lee Fisher, PhD

View on ClinicalTrials.gov

Summary

The goal of this study is to verify whether electrical stimulation of the cervical spinal cord can activate muscles of the arm and hand in people with hemiplegia following stroke. Participants will undergo a surgical procedure to implant a system which provides epidural electrical stimulation (EES) of the cervical spinal cord. Researchers will quantify the ability of EES to recruit arm and hand muscles and produce distinct kinematic movements. The implant will be removed after less than 30 days. Results of this study will provide the foundation for future studies evaluating the efficacy of a minimally-invasive neuro-technology that can be used in clinical neurorehabilitation programs to restore upper limb motor function in people with subcortical strokes, thereby increasing independence and quality of life.

Key Details

Gender

All

Age Range

21 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

8

Start Date

2021-03-24

Completion Date

2025-06-30

Last Updated

2026-09-28

Healthy Volunteers

No

Interventions

DEVICE

Epidural electrical stimulation (EES) of the cervical spinal cord

All participants enrolled in this group will undergo a surgical procedure to implant a system which provides epidural electrical stimulation (EES) of the cervical spinal cord. Researchers will quantify the ability of EES to recruit arm and hand muscles and produce distinct kinematic movements. The implant will be removed after less than 30 days.

Locations (1)

University of Pittsburgh

Pittsburgh, Pennsylvania, United States