Clinical Research Directory

Inclusion Criteria: * Primary HCC diagnosed by a surgeon and/or radiologist and oncologist according to the international guidelines for the management of HCC or by pathology * Unfeasible or refusing to undergo other treatments; * Residual normal liver volume ≥700 cc; * With decompensated cirrhosis (Child-Pugh B or C classification); * Without portal vein tumor thrombus; * Eastern Cooperative Oncology Group (ECOG) score 0-1; * Distances between tumor and normal organs (esophagus, stomach, duodenum, bowel) are more than 5 mm； * Rejecting other therapies such as resection, liver transplantation, etc. * Platelet count≥50 × 109/L, white blood count≥1.5 × 109/L; * Patients infected with hepatitis B virus who are treated with adefovir or entecavir; patients infected with hepatitis C virus whose HCV DNA are negative. Exclusion Criteria: * With Tumor thrombus； * With extrahepatic metastasis; * With lymph node involvement.