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WITHDRAWN
NCT04515901
NA

Spenopalatine Ganglion Block for Treatment of Post-dural Puncture Headaches

Sponsor: McMaster University

View on ClinicalTrials.gov

Summary

Postdural puncture headache (PDPH) is a severe, debilitating complication of dural puncture that can arise from insertion of an epidural or spinal needle for labour analgesia. Presently, the conservative treatment options for PDPH have limited effectiveness and the gold standard treatment for PDPH, an epidural blood patch, is an invasive intervention with the potential for serious complications. There is a growing number of case reports and retrospective studies that suggest a sphenopalatine ganglion block (SPGB) with local anesthetic may offer an effective, safe, and easy-to-administer treatment option for PDPH in postpartum patients. We aim to conduct a feasibility study to assess whether a randomized controlled trial is feasible comparing whether early intervention SPGB with the option for repeat, patient self-administered SPGBs versus current standard conservative management can reduce the severity and duration of PDPH pain and improve patient functional status.

Official title: Early Intervention Sphenopalatine Ganglion Blocks (SPGBs) Versus Standard Conservative Management of Post Dural Puncture Headache in Obstetric Patients - A Randomized Feasibility Study

Key Details

Gender

FEMALE

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

0

Start Date

2021-12-01

Completion Date

2022-11-11

Last Updated

2026-07-07

Healthy Volunteers

No

Interventions

DRUG

2% lidocaine

Viscous lidocaine

OTHER

Placebo

Methylcellulose and cherry flavouring

Locations (1)

McMaster University Medical Centre

Hamilton, Ontario, Canada