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Spenopalatine Ganglion Block for Treatment of Post-dural Puncture Headaches
Sponsor: McMaster University
Summary
Postdural puncture headache (PDPH) is a severe, debilitating complication of dural puncture that can arise from insertion of an epidural or spinal needle for labour analgesia. Presently, the conservative treatment options for PDPH have limited effectiveness and the gold standard treatment for PDPH, an epidural blood patch, is an invasive intervention with the potential for serious complications. There is a growing number of case reports and retrospective studies that suggest a sphenopalatine ganglion block (SPGB) with local anesthetic may offer an effective, safe, and easy-to-administer treatment option for PDPH in postpartum patients. We aim to conduct a feasibility study to assess whether a randomized controlled trial is feasible comparing whether early intervention SPGB with the option for repeat, patient self-administered SPGBs versus current standard conservative management can reduce the severity and duration of PDPH pain and improve patient functional status.
Official title: Early Intervention Sphenopalatine Ganglion Blocks (SPGBs) Versus Standard Conservative Management of Post Dural Puncture Headache in Obstetric Patients - A Randomized Feasibility Study
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
0
Start Date
2021-12-01
Completion Date
2022-11-11
Last Updated
2026-07-07
Healthy Volunteers
No
Conditions
Interventions
2% lidocaine
Viscous lidocaine
Placebo
Methylcellulose and cherry flavouring
Locations (1)
McMaster University Medical Centre
Hamilton, Ontario, Canada