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Circulating Tumor Cells (CTC) in Cancer
Sponsor: University Hospital, Basel, Switzerland
Summary
This observational study with circulating tumor cells (CTC) count, isolation and analysis at several time points during disease progression is to investigate the role and biology of CTCs and clusters of CTCs in different cancer types. It also evaluates the role of CTCs as biomarkers, and aims at the identification of key signaling networks that are active in CTCs.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
3000
Start Date
2020-10-01
Completion Date
2030-08
Last Updated
2025-03-12
Healthy Volunteers
No
Conditions
Interventions
Blood samples
Blood samples (3 ethylenediaminetetraacetic acid (EDTA) tubes with a volume of 7.5 ml blood each) will be processed for CTC isolation and characterization, ranging from molecular analysis to culture and drug screen.
Samples from tumor draining vessels
In case of tumor resection, 3 EDTA tubes (5 ml) will be withdrawn from the tumor draining vessels for CTC isolation and characterization, ranging from molecular analysis to culture and drug screen.
Locations (2)
University Hospital Basel
Basel, Switzerland
Department Oncology, Haematology & Immuntherapy, Kantonsspital Baselland
Liestal, Switzerland