Clinical Research Directory
Browse clinical research sites, groups, and studies.
Dumping Syndrome and Esophageal Atresia
Sponsor: University Hospital, Lille
Summary
Dumping syndrome (DS) is frequent in oesophageal atresia (29%). In causing hypoglycaemia, it can be dangerous for neonates. Mechanisms of DS are actually partialy understood. This is also an affection difficult to diagnose, because it only occurs after meals and can be inconstantly present. To date, their is only symptomatic treatment for DS. This study aims to understand its pathological mechanisms so as to better treat it and avoid its consequences. Oesophageal atresia patients enrolled in this study will benefit from a continuous glycemic monitoring, a continuous cardiac monitoring, and an a gastric emptying scintigraphy at the age of 3 months
Official title: Physiopathology of Dumping Syndrome in Esophageal Atresia
Key Details
Gender
All
Age Range
2 Months - 3 Months
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2024-02-23
Completion Date
2026-11
Last Updated
2025-12-23
Healthy Volunteers
No
Conditions
Interventions
Glycemic Holter
Continuous glycaemia monitoring,
gastric emptying scintigraphy
Fasting administration of a Technecium-labelled milk bottle and quantification of the remaining radioactivity by a camera every 30 minutes for 4 hours.
Holter ECG
continuous cardiac monitoring
Locations (2)
Hôpital Jeanne de Flandres
Lille, France
Hôpital Jeanne de Flandre - Pôle enfant, CHU de Lille
Lille, France