Clinical Research Directory
Browse clinical research sites, groups, and studies.
Diagnostic Role of the "White Test" With Lipidic Solution in the Early Intraoperative Identification of Open Bile Ducts for the Prevention of Bile Leakage After Liver Resection (BiLe -Trial)
Sponsor: Giulia Manzini
Summary
Bile leakage (BL) is the most frequent complication after liver resection. This study is to investigate the role of intraoperative administration of SMOFlipid 20% (fat emulsion which allows intraoperative identification of open bile ducts at the liver resection surface when it is administered retrograde through the cystic duct) in terms of prevention of postoperative BL within 30 days after surgery.
Official title: Diagnostic Role of the "White Test" With Lipidic Solution in the Early Intraoperative Identification of Open Bile Ducts for the Prevention of Bile Leakage After Liver Resection- A Randomized Controlled Multicentric Superiority Trial- The BiLe-Trial (Bile Leakage Trial)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
210
Start Date
2021-03-25
Completion Date
2025-12
Last Updated
2025-03-14
Healthy Volunteers
No
Conditions
Interventions
"white" test" (= the administration of SMOFlipid retrograde through the cystic duct)
"white" test" (= the administration of SMOFlipid retrograde through the cystic duct)
Locations (5)
Department of Visceral Surgery, Cantonal Hospital of Aarau
Aarau, Switzerland
Clarunis Basel, Universitäres Bauchzentrum Basel
Basel, Switzerland
Kantonsspital Luzern
Lucerne, Switzerland
Ospedale Regionale di Lugano
Lugano, Switzerland
Kantonsspital St. Gallen
Sankt Gallen, Switzerland