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A Pilot Study of Ciprofloxacin Plus Gemcitabine and Nab-Paclitaxel Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.
Sponsor: National University Hospital, Singapore
Summary
This is a single-center, pilot study evaluating the addition of Ciprofloxacin (study drug) to standard-of-care gemcitabine and nab-paclitaxel chemotherapy in treatment-naïve metastatic PDAC patients. Patients who are recommended gemcitabine and nab-paclitaxel chemotherapy as a standard-of-care by their treating physician will be offered to participate in this study.
Key Details
Gender
All
Age Range
21 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2019-02-22
Completion Date
2027-02
Last Updated
2025-09-25
Healthy Volunteers
No
Interventions
Ciprofloxacin
Subjects enrolled will be administered oral ciprofloxacin twice a day throughout the course of each 28-day cycle of gemcitabine and nab-paclitaxel chemotherapy.
Locations (1)
National University Hospital
Singapore, Singapore