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RECRUITING
NCT04528446

The Impact of Glomerular Disorders on Bone Quality and Strength

Sponsor: Columbia University

View on ClinicalTrials.gov

Summary

The primary objectives of this study are to: (1) determine the impact of glomerular disease on bone strength and (2) investigate the pathophysiologic underpinnings of impaired bone strength in glomerular disease.

Key Details

Gender

All

Age Range

5 Years - 55 Years

Study Type

OBSERVATIONAL

Enrollment

270

Start Date

2019-06-14

Completion Date

2024-12

Last Updated

2024-07-01

Healthy Volunteers

Yes

Interventions

RADIATION

Dual-energy X-ray absorptiometry

DXA whole body, hip, spine, and radius at baseline, and 12-month visit.

RADIATION

High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT)

HR-pQCT of the radius and tibia at baseline, and 12-month visit.

OTHER

Blood draw and Urine collection

The blood draw can be completed +/- 3 weeks from baseline or 12-month visit.

OTHER

Questionnaires

Questionnaires regarding fracture history, physical activity and dietary intake at baseline, and 12-month visit.

Locations (2)

Columbia University Irving Medical Center

New York, New York, United States

The Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States