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The Impact of Glomerular Disorders on Bone Quality and Strength
Sponsor: Columbia University
Summary
The primary objectives of this study are to: (1) determine the impact of glomerular disease on bone strength and (2) investigate the pathophysiologic underpinnings of impaired bone strength in glomerular disease.
Key Details
Gender
All
Age Range
5 Years - 55 Years
Study Type
OBSERVATIONAL
Enrollment
270
Start Date
2019-06-14
Completion Date
2024-12
Last Updated
2024-07-01
Healthy Volunteers
Yes
Interventions
Dual-energy X-ray absorptiometry
DXA whole body, hip, spine, and radius at baseline, and 12-month visit.
High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT)
HR-pQCT of the radius and tibia at baseline, and 12-month visit.
Blood draw and Urine collection
The blood draw can be completed +/- 3 weeks from baseline or 12-month visit.
Questionnaires
Questionnaires regarding fracture history, physical activity and dietary intake at baseline, and 12-month visit.
Locations (2)
Columbia University Irving Medical Center
New York, New York, United States
The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States