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Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Group 1)
Sponsor: Benjamin Viglianti
Summary
This exploratory, first-in-man, phase 0 study will evaluate the feasibility of using a sub-therapeutic dose of a fluorine-18 analogue of NP-59 (\[18F\]FNP-59) to image the adrenal gland in healthy normal subjects. The researchers believe that \[18F\]FNP-59 would greatly improve the imaging characteristics, by providing a PET imaging cholesterol analogue with significantly improved radiation dosimetry.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
6
Start Date
2021-01-18
Completion Date
2026-12
Last Updated
2025-12-05
Healthy Volunteers
Yes
Conditions
Interventions
FNP-59
FNP-59, a radiotracer, is administered for PET/CT scans.
Locations (1)
University of Michigan
Ann Arbor, Michigan, United States