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Multimodal Neuroprognostication in Disorders of Consciousness
Sponsor: Assistance Publique - Hôpitaux de Paris
Summary
Disorders of consciousness frequently occur at the acute phase of brain injuries. For the most severe cases, consciousness impairment can be prolonged. To optimize the medical plan and the goal of care, it is fundamental to have precise tools to predict chances of recovery of consciousness and potential disability. Currently, multimodal assessment including behavioral, neurophysiological and neuroimaging technics is recommended. However, the respective predictive values of these markers are poorly understood and decision making is challenging when results are contradictory
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2020-09-09
Completion Date
2027-05
Last Updated
2024-02-05
Healthy Volunteers
No
Conditions
Interventions
repeated neurological, behavioral assessments and conventional, quantitative and functional brain imagery
Based on the collected data, we will evaluate the respective diagnostic accuracy of all the markers acquired in clinical practice regarding the clinical outcome at 2 years.
Locations (1)
Hôpital Pitié Salpétrière
Paris, France