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ACTIVE NOT RECRUITING
NCT04536675
PHASE3

Effect of Perioperative Bronchodilator in COPD Patients Undergoing Lung Cancer Surgery

Sponsor: Samsung Medical Center

View on ClinicalTrials.gov

Summary

This is a double-blind randomized controlled trial evaluating the effect of perioperative dual bronchodilator therapy on post-operative pulmonary function and health-related quality of life (QoL) in mild-to-moderate less symptomatic COPD patients undergoing lung cancer surgery. Investigators hypothesized that dual bronchodilator, as compared with placebo, would prevent reduction of pulmonary function after surgical resection and improve postoperative health related QoL.

Official title: Effect of Perioperative Fixed-dose Dual Bronchodilator Therapy on Post-operative Pulmonary Function Among Mild- to -Moderate COPD Patients Undergoing Lung Cancer Surgery

Key Details

Gender

All

Age Range

40 Years - Any

Study Type

INTERVENTIONAL

Enrollment

204

Start Date

2021-04-01

Completion Date

2026-09

Last Updated

2026-06-26

Healthy Volunteers

No

Interventions

DRUG

Vilanterol and Umeclidinium Bromide

Perioperative inhaler therapy with VI/UME (Vilanterol 25mcg/Umeclidinium 62.5mcg) once daily using Ellipta device from at least for 2 weeks preoperatively to at least 16 weeks post operatively.

DRUG

Placebo

Perioperative inhaler therapy with placebo once daily using Ellipta device from at least for 2 weeks preoperatively to at least 16 weeks post operatively.

Locations (1)

Samsung Medical Center

Seoul, South Korea