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ACTIVE NOT RECRUITING
NCT04543773
NA

Individualized Targeting and Neuromodulation of Late-Life Depression

Sponsor: University of New Mexico

View on ClinicalTrials.gov

Summary

An open-label, single-arm, clinical research study about how to make transcranial magnetic stimulation (TMS), an FDA-approved treatment, more effective for patients with late-life depression using fMRI.

Key Details

Gender

All

Age Range

60 Years - 79 Years

Study Type

INTERVENTIONAL

Enrollment

24

Start Date

2024-10-01

Completion Date

2026-07-01

Last Updated

2026-01-08

Healthy Volunteers

No

Interventions

DEVICE

rTMS

rTMS will be delivered to the fMRI-determined DLPFC hotspot according to conventional parameters for clinical treatment (e.g., excitatory: 75 trains of 40 pulses, 10Hz, up to 3000 pulses). Magnetic field strength will be up to 120% of resting motor threshold. Ramp up of magnetic field strength may be utilized in the first week for tolerability. Side effects will be monitored and coil angle adjusted to improve tolerability if necessary.

Locations (1)

University of New Mexico HSC

Albuquerque, New Mexico, United States