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Ketamine-enhanced Prolonged Exposure Therapy in PTSD
Sponsor: VA Office of Research and Development
Summary
The purpose of this study is to test the safety and efficacy of repeated doses of ketamine as compared to placebo to reduce symptoms of Posttraumatic Stress Disorder (PTSD) among Veteran receiving Prolonged Exposure Therapy.
Official title: Repeated Ketamine Treatment to Accelerate Efficacy of Prolonged Exposure in PTSD
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
73
Start Date
2021-03-09
Completion Date
2025-10-07
Last Updated
2026-08-11
Healthy Volunteers
No
Conditions
Interventions
Ketamine
FDA approved anesthetic medication with rapid acting antidepressant effects.
Midazolam
FDA approved sedative medication with dissociative effects.
Locations (1)
Minneapolis VA Health Care System, Minneapolis, MN
Minneapolis, Minnesota, United States