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ACTIVE NOT RECRUITING
NCT04565821
NA

Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe

Sponsor: Massachusetts General Hospital

View on ClinicalTrials.gov

Summary

The purpose of this study is to examine the feasibility of using a trans-nasal IPD probe as a measurement tool for gut permeability

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

15

Start Date

2020-11-12

Completion Date

2028-04-30

Last Updated

2025-10-22

Healthy Volunteers

Yes

Interventions

DEVICE

IPD Probe via TNIT

A total of 10 healthy adult volunteers will be enrolled in this study. All consented participants will be receive the same intervention. A Nasal tube will be inserted through nares until reaching the small intestine. This will be confirmed by m-mode OCT. Once secured, we will start infusing Ionic solution into the intestine so that IPD Probe can measure the potential difference between this and the control reading. The control reading is measured by infusing the same ionic solution subcutaneously on large muscle groups.

Locations (1)

Massachusetts General Hospital

Boston, Massachusetts, United States