Clinical Research Directory
Browse clinical research sites, groups, and studies.
Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe
Sponsor: Massachusetts General Hospital
Summary
The purpose of this study is to examine the feasibility of using a trans-nasal IPD probe as a measurement tool for gut permeability
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2020-11-12
Completion Date
2028-04-30
Last Updated
2025-10-22
Healthy Volunteers
Yes
Conditions
Interventions
IPD Probe via TNIT
A total of 10 healthy adult volunteers will be enrolled in this study. All consented participants will be receive the same intervention. A Nasal tube will be inserted through nares until reaching the small intestine. This will be confirmed by m-mode OCT. Once secured, we will start infusing Ionic solution into the intestine so that IPD Probe can measure the potential difference between this and the control reading. The control reading is measured by infusing the same ionic solution subcutaneously on large muscle groups.
Locations (1)
Massachusetts General Hospital
Boston, Massachusetts, United States