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Study of Gastrointestinal Dysfunction and Enteric Neural Pathology in Patients With Parkinson's Disease
Sponsor: Massachusetts General Hospital
Summary
The goal of this research is to determine (1) the feasibility of tethered capsule OCT esophageal imaging in the Parkinson's Disease population; (2) the morphologic changes in the enteric nervous system of the esophagus in patients with Parkinson's disease.
Key Details
Gender
All
Age Range
40 Years - 85 Years
Study Type
OBSERVATIONAL
Enrollment
20
Start Date
2019-05-04
Completion Date
2029-12-31
Last Updated
2025-10-22
Healthy Volunteers
No
Conditions
Interventions
OCT - TCE
Participants will be asked to swallow the TCE. They may use mild numbing spray, and lubrication spray to help swallowing. Imaging will be conducted once the TCE is past the pharynx. We will advance the TCE until the stomach and then slowly pull the TCE back up the esophagus. This may be repeated twice.
Locations (1)
Massachusetts General Hospital
Boston, Massachusetts, United States