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KARMA Kontrast Evaluating Contrast Enhanced Mammography in Early Detection of Breast Cancer
Sponsor: Karolinska Institutet
Summary
Women taking part in the National Mammography Screening Program, examined at Södersjukhuset Breast Centre at Södra station in Stockholm and recalled because of suspicion of breast cancer will be invited to participate. A Contrast Enhanced Mammography will be added to the standard of care procedures for investigating a suspicion of breast cancer and blinded from each other 2 radiologists will evaluate either the Contrast Enhanced Mammography or the standard of care examinations. When comparing the potentially extra findings with Contrast Enhanced Mammography will be calculated. Potential side effects together with the patient experience will also be evaluated.
Official title: KARMA Kontrast - a Controlled Clinical Trial Evaluating Contrast Enhanced Mammography in Early Detection of Breast Cancer
Key Details
Gender
FEMALE
Age Range
25 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2021-10-01
Completion Date
2024-12-12
Last Updated
2026-08-26
Healthy Volunteers
No
Conditions
Interventions
Contrast Enhanced Mammography
A modality for examining breast conditions which is already approved and used but the evaluation of its role in a recalled screening population is limited. Intravenous iodine contrast is given prior to the mammogram.
Locations (1)
Bröstcentrum, Södersjukhuset
Stockholm, Sweden