Clinical Research Directory

Inclusion Criteria: * Patients with symptomatic irreversible pulpitis with/without mechanical allodynia * Patients with moderato to severe spontaneous pain * Mandibular molars * Patients with the ability to understand and use the pain scale * Patients accepting enrollment in the study Exclusion Criteria: * Patients allergic to any medication or material to be used in the study * Pregnant and lactating females * Patients taking medications affecting pain perception in the last 12 hours * Patients having more than one symptomatic molar in the same quadrant * Patients with contributory medical history (ASA \> II)