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Anti-αIIbβ3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti-αIIbβ3 Antibodies Study (TAAS)
Sponsor: University Hospital, Bordeaux
Summary
This project aim to correlate risk factors (genetic, therapeutic and socio-demographic factors) to anti-αIIbβ3 antibodies formation following blood products transfusion (platelets or packed red cells) or pregnancy in a national cohort of GT patients.
Key Details
Gender
All
Age Range
6 Years - Any
Study Type
INTERVENTIONAL
Enrollment
28
Start Date
2021-01-06
Completion Date
2023-07-06
Last Updated
2026-05-22
Healthy Volunteers
No
Conditions
Interventions
Antibodies screening
All included GT patients will be enrolled from different national centres during a 6 months period. Antibodies screening will be systematically realized every six months (+/- 2 weeks) and after each last blood transfusion at 7-10 days and one month (+/- 2 weeks), during a period of 18 months.
Locations (7)
CHU Bordeaux - Hôpital Haut-Lévêque
Bordeaux, France
CHU Bordeaux - Hôpital Pellegrin
Bordeaux, France
Hôpital Bicêtre, APHP
Le Kremlin-Bicêtre, France
Hôpital la Timone, APHM
Marseille, France
CHU Nîmes
Nîmes, France
CHU Strasbourg
Strasbourg, France
CHU Toulouse
Toulouse, France