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COMPLETED
NCT04595617
NA

Anti-αIIbβ3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti-αIIbβ3 Antibodies Study (TAAS)

Sponsor: University Hospital, Bordeaux

View on ClinicalTrials.gov

Summary

This project aim to correlate risk factors (genetic, therapeutic and socio-demographic factors) to anti-αIIbβ3 antibodies formation following blood products transfusion (platelets or packed red cells) or pregnancy in a national cohort of GT patients.

Key Details

Gender

All

Age Range

6 Years - Any

Study Type

INTERVENTIONAL

Enrollment

28

Start Date

2021-01-06

Completion Date

2023-07-06

Last Updated

2026-05-22

Healthy Volunteers

No

Interventions

BIOLOGICAL

Antibodies screening

All included GT patients will be enrolled from different national centres during a 6 months period. Antibodies screening will be systematically realized every six months (+/- 2 weeks) and after each last blood transfusion at 7-10 days and one month (+/- 2 weeks), during a period of 18 months.

Locations (7)

CHU Bordeaux - Hôpital Haut-Lévêque

Bordeaux, France

CHU Bordeaux - Hôpital Pellegrin

Bordeaux, France

Hôpital Bicêtre, APHP

Le Kremlin-Bicêtre, France

Hôpital la Timone, APHM

Marseille, France

CHU Nîmes

Nîmes, France

CHU Strasbourg

Strasbourg, France

CHU Toulouse

Toulouse, France