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RECRUITING
NCT04600089
PHASE2

Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI

Sponsor: Sam Tyagi

View on ClinicalTrials.gov

Summary

The objective of this study is to identify the opioid-sparing effects, and pain-reduction potential of low dose, sub-dissociative ketamine on patients undergoing thoracic endovascular aortic repair (TEVAR) procedures receiving naloxone continuous infusion (NCI).

Official title: A Randomized, Double-blind, Placebo-controlled, Study to Identify the Opioid-sparing Effects, and Pain-reduction Potential of Low Dose Ketamine on Patients Undergoing TEVAR Procedures Receiving NCI

Key Details

Gender

All

Age Range

18 Years - 90 Years

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2020-12-08

Completion Date

2027-08

Last Updated

2025-10-20

Healthy Volunteers

No

Interventions

DRUG

Saline

Saline infusion

DRUG

Ketamine

Continuous ketamine infusion at a dose of 0.2 mg/kg/hr, initiated at the induction of anesthesia and continued for 48 hours postoperatively.

Locations (1)

University of Kentucky Medical Center

Lexington, Kentucky, United States