Clinical Research Directory
Browse clinical research sites, groups, and studies.
Investigation of Subclinical Markers of Multiple Sclerosis
Sponsor: University of Split, School of Medicine
Summary
Transcranial magnetic stimulation (TMS) studies reported consistent and substantial impairments in the central nervous system (CNS) in multiple sclerosis (MS). Studies of peripheral nervous system (PNS) function comprising electromyoneurography (EMNG) reported impairments of the PNS in MS that were less pronounced and inconsistent. Neurophysiological studies are generally small and cross-sectional and with the poor grouping of MS patients according to MS type. The objective of the study is to investigate clinical, neurophysiological, and immunological markers in relapsing-remitting MS patients, and in patients with relapsing-remitting MS treated with immunomodulation. The results of the study may contribute to a better understanding of the pathophysiology of multiple sclerosis and can provide guidance in the diagnosis and treatment of patients with relapsing-remitting MS.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2020-11-23
Completion Date
2028-12-31
Last Updated
2023-10-02
Healthy Volunteers
Not specified
Interventions
1. Clinical testing; 2. Neurophysiological examination (TMS, EMNG); 3. Psychomotor examination; 4. Neuropsychological evaluation; 5. Flow cytometry; 6. ELISA
All groups will not have the same intervention. Interventions are listed and numbered for each group.
Locations (1)
University of Split School of Medicine
Split, Croatia