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Safety, Activity and Cell Kinetics of CYAD-211 in Patients With Relapsed or Refractory Multiple Myeloma
Sponsor: Celyad Oncology SA
Summary
The purpose of the IMMUNICY-1 study is to assess the safety, activity and cell kinetics of CYAD-211 in adults with relapsed or refractory multiple myeloma after a lymphodepletion regimen with fludarabine and/or cyclophosphamide
Official title: Open-label Phase I, Multi-center Study to Determine the Recommended Dose of CYAD-211 After a Non-myeloablative Preconditioning Chemotherapy in Multiple Myeloma Patients With Relapsed or Refractory Disease
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
18
Start Date
2020-11-16
Completion Date
2037-02
Last Updated
2023-08-31
Healthy Volunteers
No
Conditions
Interventions
CYAD-211
Allogeneic anti-BCMA chimeric antigen receptor (CAR) T-cell
Endoxan
Preconditioning chemotherapy
Fludara
Preconditioning chemotherapy
Locations (5)
H. Lee Moffitt Cancer Center
Tampa, Florida, United States
Nyu Langone Hospitals
New York, New York, United States
Universitair Ziekenhuis Antwerpen
Antwerp, Belgium
Institut Jules Bordet
Brussels, Belgium
AZ DELTA
Roeselare, Belgium