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ACTIVE NOT RECRUITING
NCT04613557
PHASE1

Safety, Activity and Cell Kinetics of CYAD-211 in Patients With Relapsed or Refractory Multiple Myeloma

Sponsor: Celyad Oncology SA

View on ClinicalTrials.gov

Summary

The purpose of the IMMUNICY-1 study is to assess the safety, activity and cell kinetics of CYAD-211 in adults with relapsed or refractory multiple myeloma after a lymphodepletion regimen with fludarabine and/or cyclophosphamide

Official title: Open-label Phase I, Multi-center Study to Determine the Recommended Dose of CYAD-211 After a Non-myeloablative Preconditioning Chemotherapy in Multiple Myeloma Patients With Relapsed or Refractory Disease

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

18

Start Date

2020-11-16

Completion Date

2037-02

Last Updated

2023-08-31

Healthy Volunteers

No

Interventions

BIOLOGICAL

CYAD-211

Allogeneic anti-BCMA chimeric antigen receptor (CAR) T-cell

DRUG

Endoxan

Preconditioning chemotherapy

DRUG

Fludara

Preconditioning chemotherapy

Locations (5)

H. Lee Moffitt Cancer Center

Tampa, Florida, United States

Nyu Langone Hospitals

New York, New York, United States

Universitair Ziekenhuis Antwerpen

Antwerp, Belgium

Institut Jules Bordet

Brussels, Belgium

AZ DELTA

Roeselare, Belgium