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Defining and Treating Depression-related Asthma
Sponsor: State University of New York at Buffalo
Summary
Depression is seen more often in people with asthma, and may lead to increased development and severity of asthma. This study will investigate whether children with depression and asthma have less allergic disease and less inflammation than children with asthma who do not have symptoms of depression. The study will also investigate whether the lungs of children with depression and asthma respond to an anticholinergic inhaler called ipratropium more than the lungs of non-depressed asthmatic children.
Official title: Defining and Treating a New Pediatric Asthma Endotype: Depression-related Asthma Mediated by the Cholinergic Pathway
Key Details
Gender
All
Age Range
7 Years - 17 Years
Study Type
INTERVENTIONAL
Enrollment
39
Start Date
2016-09-09
Completion Date
2019-03-11
Last Updated
2026-04-23
Healthy Volunteers
No
Conditions
Interventions
Ipratropium Bromide
All subjects receive inhaled ipratropium once with measurement of spirometry before and after. Bronchodilator response of subjects with depression is compare to that of subjects without depression.
Locations (1)
Women and Children's Hospital of Buffalo
Buffalo, New York, United States