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The Effect of Negative Pressure Wound Therapy on Wound Healing in Major Amputations of the Lower Limb
Sponsor: University of Southern Denmark
Summary
The socioeconomic costs of problematic and delayed wound healing following lower limb amputations are enormous to the society. Lower limb amputations is one of the longest known surgical treatments, but also one of the least investigated in the field of medical science. Negative Pressure Wound Therapy (NPWT) has emerged as a great instrument to aid healing. Studies have shown that it has a positive and measurable effect on wound healing following eg. total Knee and hip replacements. The aim of this study is to evaluate the effect of a closed NPWT on incidence of postoperative wound complications, in patients undergoing lower extremity amputation.
Official title: The Effect of Negative Pressure Wound Therapy on Wound Healing in Major Amputations
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2021-11-01
Completion Date
2025-07
Last Updated
2025-03-18
Healthy Volunteers
No
Interventions
PICO VAC
PICO14 device from Smith and Nephew - Off the shelf, disposable negative pressure wound therapy device. Contains sterile dressing as well as an attached small (pager-sized) suction device/canister and provides a negative pressure of -80 mmHg for 14 days.
Standard care
Sterile surgical silicone foam dressing and soft dressing applied immediately postoperative and removed after 12 days
Locations (1)
Sygehus Soenderjylland
Aabenraa, Denmark