Clinical Research Directory
Browse clinical research sites, groups, and studies.
Mediastinal Lymph Node Dissection Versus Spared Mediastinal Lymph Node Dissection in Stage I GGN NSCLC
Sponsor: Tianjin Medical University Cancer Institute and Hospital
Summary
Lung cancer is the leading cause of cancer related death worldwide. Lobectomy or sub-lobectomy with mediastinal lymph node dissection is the standard surgery. About 50% lung nodules are pure ground-glass or part-solid nodules. Non-solid nodules rarely develop mediastinal lymph node metastasis. The present study is a prospective, multicenter and randomized clinical trial, comparing the overall survival and disease-free survival of whether performing mediastinal lymph node dissection in non-small cell lung cancer with ground-glass nodule CT features.
Official title: Mediastinal Lymph Node Dissection Versus Spared Mediastinal Lymph Node Dissection in Stage IA Non-small Cell Lung Cancer Presented as Ground-glass Nodules: Study Protocol of a Phase III, Randomized, Multi-center Trial (MELDSIG) in China
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
1362
Start Date
2022-05-01
Completion Date
2029-05-01
Last Updated
2023-09-28
Healthy Volunteers
No
Conditions
Interventions
Systemic mediastinal lymph node dissection
Systematic hilar and mediastinal lymph node dissection.
Spared mediastinal lymph node dissection
Mediastinal lymph node is spared in this group.
Locations (1)
Ethics review board of Tianjin Medical University Cancer Institute and Hospital
Tianjin, Tianjin Municipality, China