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Physical Capacity in Hodgkin Lymphoma Survivors
Sponsor: University of Sao Paulo General Hospital
Summary
The study aims to investigate if physical capacity obtained in the cardiopulmonary exercise test can predict cardiovascular alterations in Hodgkin Lymphoma (HL) Survivors. In addition, to study the effects of exercise training on physical capacity and cardiovascular responses in these patients.
Official title: Physical Capacity Evaluation and Effects of ExerciseTraining on Hodgkin Lymphoma Survivors
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2017-10-21
Completion Date
2023-10-21
Last Updated
2026-05-04
Healthy Volunteers
No
Interventions
Physical Characteristics
Body Weight, Height
Assessment of Heart rate variability
Holter 24h
Blood Pressure and Cardiac Autonomic Control
Non-invasive photoplethysmography (Finometer® PRO) monitored by the electrocardiogram and respiratory frequency by a piezoelectric chest strap.
Evaluation of Baroreflex Control
The magnitude and latency of the baroreflex control of the heart rate will be assessed by bivariate analysis using the autoregressive method.
Cardiac Function and Structure
Echocardiogram
Assessment of Coronary Anatomy and Calcium Score
Angiotomography
Blood Assessments
Serum and Plasma will be extracted by centrifugation. NT-pro BNP (Roche™) and c-TnI (imunoassay Elecys 2010).
Physical Capacity
Cardiopulmonary Exercise Test.
Physical Training
Aerobic exercise: 48 sessions of 60 minutes: 5 minutes of warm-up, 40 minutes of exercise. Resistance exercise: 10 minutes of exercise and 5 minutes of recovery.
Locations (1)
Luciana de Souza Santos
São Paulo, São Paulo, Brazil