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COMPLETED
NCT04640545
PHASE1

A Study to Assess LBL-007 in Combination With Toripalimab and Axitinib Tablets Subjects With Advanced Melanoma

Sponsor: Nanjing Leads Biolabs Co.,Ltd

View on ClinicalTrials.gov

Summary

A phase I clinical study evaluating LBL-007 in the treatment of subjects with advanced solid tumors

Official title: A Phase I Multi-center Study to Evaluate the Safety ,Tolerability and Efficacy of LBL-007 Combined With Toripalimab or LBL-007 Combined With Toripalimab and Axitinib Tablets in the Treatment of Unresectable or Metastatic Melanoma

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

79

Start Date

2020-05-12

Completion Date

2024-08-19

Last Updated

2026-05-13

Healthy Volunteers

No

Interventions

DRUG

LBL-007

LBL-007 will be administered intravenously every two weeks (Q2W) .

DRUG

Toripalimab

Toripalimab Injection will be administered by intravenously (Q2W) .

DRUG

Axitinib Tablets

Axitinib Tablets On-demand administration

Locations (7)

Beijing Cancer Hospital

Beijing, Beijing Municipality, China

Fujian Cancer Hospital

Fuzhou, Fujian, China

Union Hospital Tongji Medical College Huazhong University of Science and Technology

Wuhan, Hubei, China

Hunan Cancer Hospital

Changsha, Hunan, China

Nanjing Drum Tower Hospital

Nanjing, Jiangsu, China

Jilin Cancer Hospital

Changchun, Jilin, China

West China Hospital of Sichuan University

Chengdu, Sichuan, China