Clinical Research Directory
Browse clinical research sites, groups, and studies.
Clinical Research of Tapering UDCA in PBC Patients With a Complete Response
Sponsor: Peking Union Medical College Hospital
Summary
This study explores the feasibility of the reducing medication regimen for Ursodeoxycholic Acid(UDCA) in the treatment of primary biliary cholangitis. The participants will be distributed randomly into two experimental groups and one control group. The two experimental groups will receive reduced dosage of UDCA at different level, while the control group will receive standard dosage of UDCA. The effect of therapy will be evaluated every three months.
Official title: Clinical Research of Tapering Ursodeoxycholic Acid in Primary Biliary Cholangitis Patients With A Complete Response
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2020-01-21
Completion Date
2025-05
Last Updated
2025-04-01
Healthy Volunteers
No
Conditions
Interventions
ursodeoxycholic acid
The two experimental groups will receive reduced dosage of UDCA at 10mg/Kg and 5mg/Kg everyday respectively, while the control group will receive standard dosage of UDCA.The treatment duration will be at least one year.
Locations (1)
Peking Union Medical College Hospital
Beijing, China