Clinical Research Directory

Inclusion Criteria: * English-speaking patients * 18-60 years of age with acute ACL injury (\<6 months from time of injury to reconstruction) and undergoing reconstruction with patellar tendon allograft * Written informed consent is obtained Exclusion Criteria: * Revision Surgery * Prior history of knee surgery * Concomitant ligamentous injury * Inability to obtain an MRI * Inability to participate in follow-up for the study * Any patient lacking decisional capability * Diagnosed musculoskeletal cancer or any diagnosed cancer, other than * musculoskeletal if not on long term remission (e.g. at least 5 years or negative biopsy at last exam), except basal cell carcinoma * Patients who are at higher risk for post-surgical bleeding (e.g., bleeding disorder taking anticoagulants except low dose aspirin) or post-surgical infection (e.g., taking immunosuppressants; have a severe infection or a history of serious infection or use of systemic steroids) * Known history of HIV, or has active Hepatitis B or active Hepatitis C * Alcohol and drug (medication) abuse * Pregnant or breast feeding women. Pregnancy as determined by a positive pregnancy test prior to procedure. Females of childbearing potential must agree to use an acceptable birth control method during study participation. * Patients that have received PRP, other platelet-based product, or investigational treatment in another cell/biologic study for the target knee in the 12 months prior to the injection procedure * Any clinically significant finding that would place the patient at health risk, impact the study, or affect the completion of the study * Any psychiatric illness that would prevent comprehension of the details and nature of the study and interfere with follow-up clinic visits