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Comparing Alkalinizing Agents Efficacy on Stone Risk in Patients on a Metabolically Controlled Diet
Sponsor: University of Texas Southwestern Medical Center
Summary
The purpose of this study is to compare over the counter and alternative prescription urinary alkalinizing agents to slow release potassium citrate in their ability to modify urinary parameters associated with stone formation.
Official title: Evaluation of Multiple Alkalinizing Agents on Urinary Stone Risk Parameters in Stone and Non-stone Formers on a Metabolically Controlled Diet
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2026-07-01
Completion Date
2027-07
Last Updated
2026-02-13
Healthy Volunteers
Yes
Conditions
Interventions
Potassium citrate
Slow release potassium citrate UroCit-K. Participants will take 20mEq twice daily.
Sodium bicarbonate
650mg tabs. Take 3 tabs twice daily.
Litholyte
One packet is taken with 170ml of water. Two packets daily.
Crystal Lite
The classic lemonade contains 21.7mEq/liter of alkali Therefore, patients will take 2 litres daily to have the 40mEq of alkali daily needed.
Potassium Bicarbonate
20 mEq tablets, one tablet twice daily
Locations (1)
University of Texas Southwestern Medical Center
Dallas, Texas, United States