Clinical Research Directory
Browse clinical research sites, groups, and studies.
4D-MRI for Precision Medicine
Sponsor: University of Virginia
Summary
The purpose of this study is to develop new ways to make medical images of the lungs and liver of adults using a technique called four-dimensional magnetic resonance imaging (4D-MRI). This technique produces three-dimensional movies of the inside of the chest and abdomen while the patient is breathing. (The fourth dimension is time!) This new way of medical imaging is being developed to help cancer patients undergoing radiation therapy. Radiation therapy is used to treat cancerous tumors. For radiation therapy to be effective, the precise size, shape, and location of the tumor within the body must be known. A particular difficulty for radiation treatment of lung and liver cancer is that the tumor moves during treatment because the patient is breathing. Therefore, tumor motion must also be incorporated into the treatment plan. This study aims to improve radiation treatment planning through better targeting and dose estimation based on 4D-MRI. Before this new imaging method can be used for radiation treatment planning, it must be tested in living, breathing volunteers.
Official title: Toward Precision Radiotherapy: Physiological Modeling of Respiratory Motion Based on Ultra-quality 4D-MRI
Key Details
Gender
All
Age Range
18 Years - 82 Years
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2020-11-05
Completion Date
2030-12-31
Last Updated
2025-03-24
Healthy Volunteers
Yes
Interventions
Magnetic Resonance Imaging
Four-dimensional MRI of torso
Locations (1)
University of Virginia
Charlottesville, Virginia, United States