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Ocular Microbiome and Immune System in Dry Eyes
Sponsor: Insel Gruppe AG, University Hospital Bern
Summary
The primary objectives of this study are the characterization of the ocular microbiome as well as of the local immune system in participants with and without dry eye disease. Secondary objectives are the identification of differences in the ocular microbiome as well as in the immune system between participants with and without dry eye disease to ultimately find associations between the ocular microbiome and the immune system in dry eye disease.
Official title: Associations of the Ocular Microbiome and the Immune System in Dry Eye Disease
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
600
Start Date
2020-10-01
Completion Date
2026-12-31
Last Updated
2025-04-01
Healthy Volunteers
Yes
Conditions
Interventions
Ocular microbiome
Taxonomical and functional characterization of the ocular microbiome
Ocular immune system
Functional characterization of the tear fluid proteome, histology of conjunctival tissue and molecular assays
Locations (1)
Department of Ophthalmology, Inselspital
Bern, Switzerland