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Mueller Polarimetric Colposcopy for High-performance Detection of Cervical Changes During Pregnancy
Sponsor: Assistance Publique - Hôpitaux de Paris
Summary
Mueller polarimetric colposcopy appears to be a powerful tool for evaluating cervical microstructure modification during pregnancy. Some polarimetric parameters of the uterine cervix can be correlated with the gestational age. The uterine cervix's polarimetric analysis could make it possible to accurately predict the term of childbirth and be used as a screening tool for preterm birth.
Official title: Mueller Polarimetric Colposcopy for High-performance Detection of Cervical Changes During Pregnancy (COLPOTERME)
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
683
Start Date
2020-12-22
Completion Date
2026-12
Last Updated
2026-01-21
Healthy Volunteers
No
Conditions
Interventions
Mueller's polarimetric colposcopy "Group 1"
Determination of the best "polarimetric biomarkers" reflecting the status of the cervical microstructure throughout its remodeling process due to the pregnancy in a population with a low-risk premature birth. This "polarimetric biomarkers" should make it possible to accurately determine the time remaining before childbirth for a normal pregnancy and, therefore, to monitor the regular advancement of the gestation.
Mueller's polarimetric colposcopy "Group 2"
Determination of the best "polarimetric biomarkers" reflecting the status of the cervical microstructure throughout its remodeling process due to the pregnancy in a population at high-risk of preterm birth. This "polarimetric biomarkers" should make it possible to accurately determine the time remaining before childbirth for an abnormal pregnancy and, therefore, to predict premature childbirth.
Locations (1)
Hospital Bicêtre - Gynecology-Obstetrics Department
Le Kremlin-Bicêtre, France, France