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iCorMicA - Stratified Medicine in Angina
Sponsor: NHS Greater Glasgow and Clyde
Summary
The iCorMicA study is a multicentre, prospective, randomised, double-blind, sham-controlled, parallel-group, end-point trial and registry. The investigators seek to determine whether stratified medical therapy guided by an adjunctive interventional diagnostic procedure (IDP) during the invasive management of patients with known or suspected angina but no obstructive coronary artery disease improves symptoms, wellbeing, cardiovascular risk and clinical outcomes.
Official title: International Study of Coronary Microvascular Angina (iCorMicA): a Randomised, Controlled, Multicentre Trial and Registry
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1500
Start Date
2020-12-30
Completion Date
2030-12-31
Last Updated
2026-04-09
Healthy Volunteers
No
Conditions
Interventions
Disclosure of IDP results
The results of the adjunctive IDP performed at time of invasive coronary angiography are made available to the catheter laboratory clinician, to aid in the diagnostic process.
IDP performed but results not disclosed
The results of the IDP performed at the time of invasive coronary angiography are concealed from the catheter laboratory clinician who will be blinded. The patient is managed according to standard of care.
Locations (39)
Mater Private Hsopital
Cork, Ireland
Mater Private Hospital
Dublin, Ireland
Radboud University Medical Centre
Nijmegen, Netherlands
5th Military Hospital
Krakow, Poland
Golden Jubilee National Hospital
Clydebank, Scotland, United Kingdom
Aberdeen Royal Hospital
Aberdeen, United Kingdom
William Harvey Hospital
Ashford, United Kingdom
Basildon University Hospital - Essex Cardiothoracic Centre
Basildon, United Kingdom
Bedford Hospital NHS Trust
Bedford, United Kingdom
Royal Victoria Hospital
Belfast, United Kingdom
Birmingham Heartlands Hospital
Birmingham, United Kingdom
Royal Blackburn Teaching Hospital
Blackburn, United Kingdom
Victoria Hospital
Blackpool, United Kingdom
Glan Clwyd Hospital
Bodelwyddan, United Kingdom
Royal Bournemouth Hospital
Bournemouth, United Kingdom
Royal Papworth Hospital NHS Foundation Trust
Cambridge, United Kingdom
University Hospital of Wales
Cardiff, United Kingdom
St Peter's Hospital NHS Foundation Trust
Chertsey, United Kingdom
University Hospitals Coventry & Warwickshire NHS Trust
Coventry, United Kingdom
University Hospital Hairmyres
East Kilbride, United Kingdom
NHS Greater Glasgow and Clyde
Glasgow, United Kingdom
Raigmore Hospital
Inverness, United Kingdom
Leeds Teaching Hospital NHS Trust
Leeds, United Kingdom
Liverpool Heart and Chest Hospital
Liverpool, United Kingdom
Royal Free Hospital
London, United Kingdom
Barts Health NHS Trust - St. Bartholomew's Hospital
London, United Kingdom
King's College Hospital
London, United Kingdom
Northwick Park Hospital
London, United Kingdom
The Newcastle upon Tyne Hospitals NHS Foundation Trust
Newcastle upon Tyne, United Kingdom
Royal Gwent Hospital
Newport, United Kingdom
Nottingham University Hospitals NHS TRUST
Nottingham, United Kingdom
Queen Alexandra Hospital
Portsmouth, United Kingdom
Northern General Hospital
Sheffield, United Kingdom
University Hospital Southampton
Southampton, United Kingdom
South Tyneside and Sunderland NHS Foundation Trust
Sunderland, United Kingdom
Morriston Hospital
Swansea, United Kingdom
Pinderfields General Hospital
Wakefield, United Kingdom
Watford general Hospital
Watford, United Kingdom
New Cross Hospital
Wolverhampton, United Kingdom