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Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone
Sponsor: Stanford University
Summary
In the US, pain management after surgery for surgical treatment of osteoarthritis at the base of the thumb typically consists of prescription opioids during the early recovery phase. Given the highly addictive nature of prescription opioids, guidelines are being evaluated by hand surgeons to reduce opioid use while still maintaining pain control after surgery. A promising approach is to use non-narcotic medication as the first line of treatment. The purpose of this study is to demonstrate the efficacy of a combination of non-steroidal anti-inflammatory drugs (NSAIDs), ibuprofen and acetaminophen, in comparison to a morphine analogue substance (oxycodone) for pain management in the first 30 days after surgery.
Official title: Pain Relief After Trapeziectomy Without Opioids: Ibuprofen & Acetaminophen Versus Oxycodone
Key Details
Gender
All
Age Range
45 Years - Any
Study Type
INTERVENTIONAL
Enrollment
121
Start Date
2021-12-27
Completion Date
2027-08
Last Updated
2025-08-06
Healthy Volunteers
No
Conditions
Interventions
NSAID capsules
1, Ibuprofen 400-mg and 1, Acetaminophen 500-mg capsule per dosage
Opioid capsule
1, Oxycodone 5-mg capsule and 1, placebo capsule per dosage
Locations (2)
Stanford Health Care
Redwood City, California, United States
University of Utah Health Care
Salt Lake City, Utah, United States