Clinical Research Directory
Browse clinical research sites, groups, and studies.
Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer
Sponsor: University of Aarhus
Summary
Study aims to determine if functional lung avoidance based on perfusion single photon emission (SPECT)/CT scan, improves toxicity outcomes for patients with advanced lung cancer undergoing chemo-radiotherapy. Functional avoidance implies a dose plan that takes functional distribution in the lung into account, and avoids highly functional lung volumes sparing them from radiation.
Official title: Functional Lung Avoidance SPECT-guided (ASPECT) Radiation Therapy for Lung Cancer Patients: Phase II Randomised Clinical Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2021-12-01
Completion Date
2028-12-01
Last Updated
2026-02-24
Healthy Volunteers
No
Conditions
Interventions
Single-photon-emission CT scan
SPECT/CT scan is an established functional modality used in the diagnosis and monitoring of lung disease. SPECT/CT scan images pulmonary circulation, where perfused areas equate with normal functional lung
Locations (2)
Sydney West Radiation Oncology Network Westmead and Blacktown Hospitals
Sydney, New South Wales, Australia
Department of Oncology, Aarhus University Hospital
Aarhus, Denmark