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RECRUITING
NCT04676828
NA

Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer

Sponsor: University of Aarhus

View on ClinicalTrials.gov

Summary

Study aims to determine if functional lung avoidance based on perfusion single photon emission (SPECT)/CT scan, improves toxicity outcomes for patients with advanced lung cancer undergoing chemo-radiotherapy. Functional avoidance implies a dose plan that takes functional distribution in the lung into account, and avoids highly functional lung volumes sparing them from radiation.

Official title: Functional Lung Avoidance SPECT-guided (ASPECT) Radiation Therapy for Lung Cancer Patients: Phase II Randomised Clinical Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2021-12-01

Completion Date

2028-12-01

Last Updated

2026-02-24

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Single-photon-emission CT scan

SPECT/CT scan is an established functional modality used in the diagnosis and monitoring of lung disease. SPECT/CT scan images pulmonary circulation, where perfused areas equate with normal functional lung

Locations (2)

Sydney West Radiation Oncology Network Westmead and Blacktown Hospitals

Sydney, New South Wales, Australia

Department of Oncology, Aarhus University Hospital

Aarhus, Denmark