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Bacteriophage Therapy in Tonsillitis
Sponsor: Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan
Summary
The patients received bacteriophage therapy with a liquid piobacteriophage complex (liquid pyobacteriophage complex - PCL). PСL was administered via nebulizer inhalation to irrigate the tonsil mucosa. A total of 5 ml of PCL was inhaled for 10 minutes every 5 days. The drug causes the lysis of certain bacteria, including staphylococcus, enterococcus, streptococcus, enteropathogenic E. coli, Proteus vulgaris, Proteus mirabilis, Pseudomonas aeruginosa, Klebsiella pneumoniae and Klebsiella oxytoca. The choice of this drug was based on bacteriological studies.
Official title: Bacteriophage Therapy in Acute Tonsillitis
Key Details
Gender
All
Age Range
3 Years - 14 Years
Study Type
INTERVENTIONAL
Enrollment
128
Start Date
2020-10-02
Completion Date
2028-12-31
Last Updated
2025-05-21
Healthy Volunteers
No
Conditions
Interventions
Nebulizer inhalation irrigation of the mucous membranes of the tonsils with a bacteriophage.
Bacteriophage therapy using a liquid complex of pyobacteriophages (pyobacteriophage complex liquid - PСL). PСL was administered via nebulizer inhalation to irrigate the mucous membranes of the tonsils. In total, 5 ml of PCL was inhaled for up to 10 minutes once every 5 days.
Locations (1)
Tashkent Pediatric Medical Institute
Tashkent, Uzbekistan