Clinical Research Directory
Browse clinical research sites, groups, and studies.
Compressed Intermittent Theta Burst Stimulation
Sponsor: University of Pennsylvania
Summary
In this proposal the investigators will use an accelerated TMS protocol that concentrates the magnetic stimulation that would usually occur over 6 weeks into 10 treatment sessions per days, for 5 consecutive days in patient with treatment-refractory depression. This protocol will build on a previously published study demonstrating clinical efficacy of intermittent theta-burst stimulation (iTBS) on left dorsolateral prefrontal cortex (L-dlPFC) in a treatment refractory population.
Official title: A Within Study on the Effects of L-dlPFC Activation Through iTBS in Refractory Depression
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2020-02-20
Completion Date
2027-01-20
Last Updated
2026-01-16
Healthy Volunteers
No
Conditions
Interventions
intermittent Theta Burst Stimulation
The present study will utilize TMS dosage of iTBS of 18 000 pulses a day for 5 consecutive days.
Locations (2)
Department of Interventional Psychiatry, University of California San Diego
La Jolla, California, United States
Center for Neuromodulation in Depression and Stress
Philadelphia, Pennsylvania, United States