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Efficacy of Placebo Versus Chlorpheniramine for the Prevention of Allergic Transfusion Reactions.
Sponsor: Institute of Hematology & Blood Diseases Hospital, China
Summary
This is a prospective, randomized, double-blind controlled trial to evaluate the efficacy of placebo versus chlorpheniramine for the prevention of allergic transfusion reactions.
Official title: A Prospective, Randomized, Double-blind Controlled Trial of Chlorpheniramine Pretransfusion Medication for Allergic Transfusion Reactions
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
6642
Start Date
2021-01-01
Completion Date
2027-06-30
Last Updated
2025-08-05
Healthy Volunteers
No
Conditions
Interventions
Placebo
The tablet resembles chlorpheniramine but has no therapeutic value.
Chlorpheniramine
An antihistamine that reduces the natural chemical histamine in the body.
Locations (4)
Anhui Provincial Hospital
Hefei, Anhui, China
Zhoukou Central Hospital
Zhoukou, Henan, China
The Second Affilated Hospital of Shandong First Medical University
Tai’an, Shandong, China
Regenerative Medicine Center
Tianjin, Tianjin Municipality, China